Panama Homes for Sale

Welcome to Panama, a charming subdivision nestled in the heart of Jacksonville, Florida, within the vibrant Duval County. This picturesque community offers a unique blend of suburban tranquility and urban convenience, making it an ideal place for families, retirees, and everyone in between.

Panama is known for its welcoming atmosphere, where neighbors become friends, and community spirit thrives. The tree-lined streets are perfect for evening strolls, and the nearby parks provide ample opportunities for outdoor activities, whether you enjoy a leisurely walk, a picnic with loved ones, or a fun-filled day with the kids at the playground.

As for the homes for sale in Panama, you’ll find a diverse selection that caters to various tastes and budgets. From charming single-family homes with spacious yards to modern townhouses with contemporary finishes, there’s something here for everyone. Many properties boast inviting open floor plans, updated kitchens, and beautifully landscaped gardens, perfect for entertaining or simply enjoying quiet evenings at home.

Living in Panama means you’re just a short drive away from the bustling downtown Jacksonville, where you can explore an array of dining, shopping, and entertainment options. With excellent schools, convenient access to major highways, and a rich cultural scene, this subdivision truly offers the best of both worlds.

If you’re looking to find your dream home in a friendly community with a wealth of amenities, Panama is the perfect place to start your journey. Explore the available homes for sale today and discover the enchanting lifestyle that awaits you in this delightful Jacksonville neighborhood!

Newest Panama Homes for Sale

$310,000

4 Beds ⋅ 2 Baths ⋅ O6425846 MLS

This spacious 4 bedroom, 2 bath home in historic V.M. Ybor district has 10 ft ceilings. Master bedroom has private bathroom and walk-in closet. The other three bedroom are spacious. Complete renovation was done in 2002. Kitchen has stainless steel appliances; home has central air conditioning and heating. You can move right in or update rooms to your liking. This home has a large front porch facing beautiful Cascaden Park. It also has a large back yard with a high yield Avocado tree and a lime tree! House needs some work especially the back yard. Price is very negotiable due to work needed. This is a great property for DIY'ers or Landlord. House passed 4-point inspection five years ago for insurance; New roof installed 4 years ago. Central Heat and Air Conditioning works great. Next door, a brand new home is being built. For Landlords, the Rent Zestimate is $3183 the last time I looked offering over a 9% cap rate with high appreciation potential. Close to Alma De Cuba club and La Secunda Bakery. Close to downtown.

1410 E 21st Avenue, Tampa

Listing courtesy of PROPERTIO. 954-418-2154

$219,000

2 Beds ⋅ 2 Baths ⋅ G5114279 MLS

Excellent investment opportunity! This well-located duplex sits on a spacious corner lot in a highly desirable area just minutes from downtown. Each unit offers strong potential, making it ideal for investors or owner-occupants looking to offset their mortgage with rental income. Prime location with excellent income potential.From

1401 E 24th Avenue, Tampa

Listing courtesy of LPT REALTY, LLC. 877-366-2213

$309,000

2 Beds ⋅ 2 Baths ⋅ TB8518643 MLS

Located in the heart of Historic Ybor City, this charming bungalow offers exceptional flexibility for both owner-occupants and investors. Just minutes from downtown Tampa, major interstates, Hillsborough Community College, local parks, restaurants, and Ybor's vibrant entertainment district, the location places some of Tampa's best amenities right at your doorstep. The main residence feels larger than its footprint, featuring an efficient, open layout with luxury vinyl flooring throughout, two spacious bedrooms, and one-and-a-half baths. The primary suite includes a private half bath and custom closet, while the full bathroom is appointed with a contemporary double-sink vanity. The updated kitchen offers modern cabinetry, newer appliances, and ample storage, creating a functional space for everyday living. Fresh interior and exterior paint add to the home's clean, move-in-ready appeal. A detached accessory structure provides additional versatility with a private bedroom, full bath, kitchenette, and separate split-system air conditioning—ideal for guests, a home office, creative studio, or income-producing opportunity. This property presents an attractive opportunity for those seeking a turnkey investment, a primary residence, or both. Additional features include replacement windows (2017), air conditioning (2016), water heater (2018), and a durable metal roof, offering long-term peace of mind. With inviting curb appeal, a welcoming front porch, and a location that continues to see strong demand, this Ybor City property offers endless potential in one of Tampa's most historic and dynamic neighborhoods.

1406 E 23rd Avenue, Tampa

Listing courtesy of SMITH & ASSOCIATES REAL ESTATE. 813-839-3800

$215,000

2 Beds ⋅ 1 Baths ⋅ TB8514668 MLS

Welcome to this charming bungalow-style corner home located in one of Tampa’s fastest-growing areas. This property features soaring ceilings, a spacious fenced backyard with extended parking, and a brand-new 2025 metal roof. Currently tenant-occupied with a Section 8 lease at $1,500/month through September 2026, offering immediate cash flow with flexibility for the new owner to renew, increase rents, or explore other opportunities including Airbnb. No HOA, no CDD, and no flood zone. Conveniently located 2 miles from Downtown Tampa, Ybor, Riverwalk, Armature Works, I-4, I-275, and the new Gasworx development. Whether you’re an investor or future homeowner, this is a prime opportunity that won’t last long! One or more photo(s) has been virtually staged.

1301 E 26th Avenue, Tampa

Listing courtesy of THE SOMERDAY GROUP PL. 813-520-9123

$220,000

3 Beds ⋅ 1 Baths ⋅ TB8514658 MLS

Virtually Staged. Buyer financing fell through! Their loss is your gain! Welcome to this charming bungalow-style home featuring soaring ceilings, updated quartz countertops, tile flooring throughout, and a versatile bonus room. Major updates include a NEW 2026 ROOF and A/C only 5 years old. Enjoy a spacious fenced backyard with extended parking, no HOA, no CDD, and no flood zone. Conveniently located just minutes from Downtown Tampa, Ybor, Riverwalk, Armature Works, I-4, and I-275. Perfect for a first-time buyer, investor, or Airbnb opportunity. Currently occupied by a month-to-month tenant, giving the next owner flexibility to continue renting, renovate, Airbnb, or move in. This deal won’t last long, schedule your private showing today! One or more photo(s) has been virtually staged.

1303 E 26th Avenue, Tampa

Listing courtesy of THE SOMERDAY GROUP PL. 813-520-9123

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